PT  - JOURNAL ARTICLE
AU  - Vinall, Maria
ED  - Schuler, Gerhard
TI  - Controversial Issues in TAVI
DP  - 2011 Nov 01
TA  - MD Conference Express
PG  - 27--28
VI  - 11
IP  - 10
4099  - http://mdc.sagepub.com/content/11/10/27.short
4100  - http://mdc.sagepub.com/content/11/10/27.full
AB  - There are three major accepted indications for transcatheter aortic valve implantation (TAVI), as well as a number of minor conditions in which TAVI may be reasonable. The first is an inoperable patient with severe aortic stenosis (mean gradient >40 mm Hg or jet velocity >4 m/sec) and surgical risk >50%. The benefit of TAVI in these patients was shown in the PARTNER trial [NCT00530894; Leon MB et al. N Engl J Med 2010], which reported a cardiovascular mortality rate after 1 year of 20.5% for TAVI patients versus 44.6% for patients who received standard therapy (p<0.001).