PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Steg, Philippe Gabriel TI - Safety and Tolerability Darexaban in Patients with ACS: The RUBY-1 Trial DP - 2011 Nov 01 TA - MD Conference Express PG - 13--14 VI - 11 IP - 10 4099 - http://mdc.sagepub.com/content/11/10/13.short 4100 - http://mdc.sagepub.com/content/11/10/13.full AB - Results from the RUBY-I trial [NCT00994292] showed a dose-related, 2- to 4-fold increase in bleeding when the factor Xa inhibitor darexaban was added to standard treatment (aspirin with or without clopidogrel) for the secondary prevention of ischemic vascular events in patients with recent acute coronary syndrome.