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- Figure 1.
Effects of Treatment with rTRAIL in Meningitis Induced By Live pneumococci in Mice.
(A) At 24 hours after infection, CSF bacterial load in untreated and rTRAIL-treated wild-type mice did not differ. (B) CSF leukocyte concentration was significantly lower in rTRAIL-treated mice than in controls. **p<0.01, Student's t-test. (C) Mortality was higher in untreated versus rTRAIL-treated mice. **p<0.01, log rank test. (D) Apoptosis was reduced by treatment with rTRAIL. **p<0.01, Student's t-test.
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The Role of Adjunctive Steroids in the Treatment of Bacterial Meningitis
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