PT - JOURNAL ARTICLE AU - Butterman, Eric ED - Zhanel, George TI - New Drugs on the Horizon to Treat MDR Pathogens DP - 2011 Dec 01 TA - MD Conference Express PG - 25--26 VI - 11 IP - 12 4099 - http://mdc.sagepub.com/content/11/12/25.short 4100 - http://mdc.sagepub.com/content/11/12/25.full AB - Aminoglycosides are a well-known class of drugs with proven efficacy; however, they are being used less frequently because of resistance, nephrotoxicity, and ototoxicity. This article discusses plazomicin (formerly ACHN-490), a new aminoglycoside that is used to treat gram-negative infections.