RT Journal Article
SR Electronic
A1 Buckley, Rita
T1 Preventing Resistance — The Role of Optimized Dosing
JF MD Conference Express
YR 2011
FD SAGE Publications
VO 11
IS 12
SP 19
OP 20
DO 10.1177/155989771112012
UL http://mdc.sagepub.com/content/11/12/19.abstract
AB The rapid emergence of antibiotic resistance is a major public health concern [Zhang L et al. Appl Environ Microbiol 2011]. This article discusses five questions of resistant bacteria in the gut: Their possible presence without antibiotic exposure; Whether there is selection of resistant gut bacteria during antimicrobial exposure; Whether there is selection of resistance during systemic treatment for other infections; Whether it is possible to avoid or minimize selection; How optimization of treatment relates to selection of resistance in the gut.