RT Journal Article SR Electronic A1 Vinall, Maria T1 Pain, the Brain, and Osteoarthritis JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 13 SP 27 OP 28 DO 10.1177/155989771113017 UL http://mdc.sagepub.com/content/11/13/27.abstract AB Data appears to demonstrate that chronic pain imparts a specific signature on the brain that is associated with functional, behavioral, and chemical changes in the cerebral cortex. The specificity of this pain signature for different clinical conditions may provide the opportunity to develop targeted therapies for osteoarthritis and other chronic painful conditions.