Summary

Behçet disease (BD) is a genetically complex condition that is characterized by recurrent inflammatory attacks that affect the orogenital mucosa, eyes, and skin. Genomewide association studies have linked the IL10 and IL23R-IL12RB2 loci to BD susceptibility [Remmers EF et al. Nat Genet 2010; Mizuki N et al. Nat Genet 2010].