PT  - JOURNAL ARTICLE
AU  - Vinall, Maria
ED  - Dees, Clara
TI  - JAK2 Reduces Basal Synthesis of Collagen in SSc Fibroblasts
DP  - 2011  01
TA  - MD Conference Express
PG  - 16--16
VI  - 11
IP  - 13
4099  - http://mdc.sagepub.com/content/11/13/16.short
4100  - http://mdc.sagepub.com/content/11/13/16.full
AB  - This article discusses a study that explored the potential role of Janus kinase 2 (JAK2) as a molecular target for the treatment of fibrotic disease. In this study, inhibition of JAK2 reduced the basal synthesis of collagen selectively in systemic sclerosis fibroblasts but not in control fibroblasts.