RT Journal Article SR Electronic A1 Vinall, Maria T1 Tofacitinib in Patients with Active RA with an Inadequate Response to Tumor Necrosis Factor Inhibitors JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 13 SP 11 OP 12 DO 10.1177/155989771113003 UL http://mdc.sagepub.com/content/11/13/11.abstract AB An oral Janus kinase inhibitor, in combination with methotrexate, led to significant improvements in a treatment-refractory rheumatoid arthritis population with no significant safety concerns. This article discusses the Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of 2 Doses of CP-690,550 In Patients With Active Rheumatoid Arthritis On Background Methotrexate With Inadequate Response to TNF Inhibitors study [ORAL Sync; NCT00960440].