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type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/cdn\/css\/http\/css_Xg7z6oCTVgud_Q0huYz9x9iiD5H_2YPSJ5z2ZViSWdY.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cdiv class=\u0022section abstract\u0022 id=\u0022abstract-1\u0022\u003E\u003Ch2\u003ESummary\u003C\/h2\u003E\n            \u003Cp id=\u0022p-1\u0022\u003EWith parental assistance and use of a spacer, young children can correctly use a novel propellant-free metered-dose inhaler to treat respiratory conditions. This article discusses the Respimat\u00ae Soft Mist\u2122 inhaler and the potentials for technical failures.\u003C\/p\u003E\n         \u003C\/div\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003Epulmonary clinical trials\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003Easthma\u003C\/li\u003E\u003C\/ul\u003E\u003Cdiv class=\u0022section\u0022 id=\u0022sec-1\u0022\u003E\n         \n         \u003Cp id=\u0022p-2\u0022\u003EWith parental assistance and use of a spacer, young children can correctly use a novel propellant-free metered-dose inhaler to treat respiratory conditions, German investigators reported.\u003C\/p\u003E\n         \u003Cp id=\u0022p-3\u0022\u003EOnly one of 99 children aged younger than 5 years did not use the Respimat\u00ae Soft Mist\u2122 inhaler correctly. Technical failure occurred as a result of the child\u0027s refusal to cooperate rather than an inability to use the inhaler, Wolfgang Kamin, MD, Children\u0027s Hospital, Hamm, Germany, and colleagues reported.\u003C\/p\u003E\n         \u003Cp id=\u0022p-4\u0022\u003EThe Respimat\u00ae Soft Mist\u2122 is a handheld, multidose, propellant-free inhalation device that generates a slow-moving cloud that contains a high, fine-particle medication dose. Because spray generation is independent of inspiratory flow, the device might afford opportunities to treat young children with respiratory disorders.\u003C\/p\u003E\n         \u003Cp id=\u0022p-5\u0022\u003ETo assess the ability of young children to use the novel inhalation device, investigators at two centers in Germany recruited 99 pediatric patients with a variety of respiratory disorders. The children were grouped by age (\u0026lt;1, 1 to \u0026lt;2, 2 to \u0026lt;3, 3 to \u0026lt;4, and 4 to \u0026lt;5 years) and their inhaler usage skills were evaluated by direct observation of the investigators.\u003C\/p\u003E\n         \u003Cp id=\u0022p-6\u0022\u003EDr. Kamin reported that all but one child aged younger than 3 years were able to use the Respimat\u00ae Soft Mist\u2122 correctly with a spacer. Additionally, 23 of 27 (85%) children aged 4 to 5 years were able to use the device correctly without a spacer, but only 12 of 30 (40%) children aged 3 to 4 could use the Respimat\u00ae Soft Mist\u2122 correctly without a spacer.\u003C\/p\u003E\n         \u003Cp id=\u0022p-7\u0022\u003EWhen paired with the spacer, all children in the 3 to 4 year and 4 to 5-year age groups could use the inhaler properly. Rates of correct usage decreased without parental assistance.\u003C\/p\u003E\n         \u003Cp id=\u0022p-8\u0022\u003E\u201cThe majority of subjects aged 4 to 5 can handle the Respimat\u00ae Soft Mist\u2122 inhaler without a spacer but with considerable variability in technique,\u201d Dr. Kamin concluded. \u201cThus, to ensure standardized dosing, children below 5 years of age are recommended to use the Respimat\u00ae Soft Mist\u2122 inhaler with a spacer.\u201d\u003C\/p\u003E\n         \u003Cp id=\u0022p-9\u0022\u003EIn general, patient and parental satisfaction with the Respimat\u00ae Soft Mist\u2122 inhaler was high, with or without the spacer. Satisfaction rates for reliability, instructions, ease of use, and overall ability to use the inhaler were 90% or higher, declining to 75% when children were handling the device alone. The Respimat\u00ae Soft Mist\u2122 inhaler plus spacer had satisfaction rates that ranged from 83% to 97% for all components of use.\u003C\/p\u003E\n      \u003C\/div\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2010 MD Conference Express\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Ca href=\u0022http:\/\/mdc.sagepub.com\/content\/10\/3\/7.2.abstract\u0022 class=\u0022hw-link hw-link-article-abstract\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView Summary\u003C\/a\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzmsr1\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}