PT - JOURNAL ARTICLE AU - Sinclair, Heather Q. ED - Domschke, Katharina TI - Neurobiologic and Psychopharmacologic Solutions for the Treatment of Depression DP - 2010 Aug 01 TA - MD Conference Express PG - 7--9 VI - 10 IP - 4 4099 - http://mdc.sagepub.com/content/10/4/7.short 4100 - http://mdc.sagepub.com/content/10/4/7.full AB - Antidepressant treatment response is dependent upon numerous individual factors, such as gender, age, disease severity, symptom type, comorbidities, and genetic factors. New advances in pharmacogenetics, neurosurgical intervention, and medications may hold the key to improving treatment response in patients with refractory depression.