RT Journal Article SR Electronic T1 Aliskiren-Based Therapy Controls Blood Pressure Regardless of Plasma Renin Activity JF MD Conference Express YR 2010 FD SAGE Publications VO 10 IS 5 SP 7 OP 7 DO 10.1177/155989771005003 UL http://mdc.sagepub.com/content/10/5/7.1.abstract AB Although aliskiren is established as an effective antihypertensive agent, it is not known whether its BP-lowering effects are dependent on baseline plasma renin activity (PRA) levels. The current prospective, open-label trial was defined to evaluate the ability of aliskiren to control BP alone and in combination with other antihypertensive medications in patients with various baseline PRA levels.