PT - JOURNAL ARTICLE AU - Vinall, Phil ED - Bonomo, Jordan TI - Dramatic Early Improvement in the NINDS Trial: Better 90 Day Outcomes and No Increased Rates of Intracranial Hemorrhage DP - 2009 Apr 01 TA - MD Conference Express PG - 17--18 VI - 9 IP - 1 4099 - http://mdc.sagepub.com/content/9/1/17.short 4100 - http://mdc.sagepub.com/content/9/1/17.full AB - This article discusses the results of a retrospective study that used data from the rt-PA arm of the National Institute of Neurological Disorders (NINDS) trial [Kwiatkowski TG et al. N Engl J Med 1999] to evaluate dramatic early improvement after treatment with IV-rt-PA as a risk factor for the development of posttreatment ICH. A secondary objective was to characterize the subgroup of patients with dramatic early improvement.