PT  - JOURNAL ARTICLE
AU  - Vinall, Maria
ED  - Molina, Carlos A.
TI  - Results of a Randomized, Multi-Center Safety Trial of Perflutren Lipid Microspheres: TUCSON
DP  - 2009 Apr 01
TA  - MD Conference Express
PG  - 15--16
VI  - 9
IP  - 1
4099  - http://mdc.sagepub.com/content/9/1/15.short
4100  - http://mdc.sagepub.com/content/9/1/15.full
AB  - Microspheres that are combined with systemic tPA and rational transcranial Doppler show promise as a recanalization tool in patients with acute ischemic stroke if administered within 3 hours of stroke onset. This article discusses results from the Transcranial Ultrasound in Clinical SONolyis [TUCSON; NCT00504842] trial, identifying 1.4 mL of MRX-801 perflutren lipid microspheres as a safe dose that produces higher rates of recanalization (67% vs 33%; p=0.22) compared with controls.