Summary

A genome wide genotyping study has identified genetic loci that contribute to intracranial aneurysm (IA) formation and rupture. Single nucleotide polymorphisms on chromosomes 2q, 8q, and 9p showed significant association with IA [Bilguvar et al. Nat Genet 2008]. This article discusses the locus' association with coronary artery disease and, more recently, with aortic aneurysm and IA.