PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Sabatine, Marc S. TI - Otamixaban May Reduce the Risk of Ischemic Events in Patients with NSTE-ACS DP - 2009 Dec 01 TA - MD Conference Express PG - 20--20 VI - 9 IP - 4 4099 - http://mdc.sagepub.com/content/9/4/20.1.short 4100 - http://mdc.sagepub.com/content/9/4/20.1.full AB - Results from the phase 2 Study Program to Evaluate the Prevention of Ischemia with Direct Xa inhibition [SEPIA-ACS1 TIMI 42; NCT00317395] study provided promising data that otamixaban, an intravenous direct Factor Xa inhibitor, at intermediate doses may be associated with a lower risk of ischemic events with similar bleeding compared with the current standard of care in patients with non-ST elevation acute coronary syndromes (NSTE-ACS) [Sabatine MS et al. Lancet 2009].