PT - JOURNAL ARTICLE AU - Jacobson, Anne ED - Yusuf, Salim TI - Irbesartan Fails to Prevent Most Vascular Events in Patients with AF DP - 2009 Dec 01 TA - MD Conference Express PG - 12--13 VI - 9 IP - 4 4099 - http://mdc.sagepub.com/content/9/4/12.2.short 4100 - http://mdc.sagepub.com/content/9/4/12.2.full AB - In the Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events [ACTIVE-I; NCT00249795], treatment with irbesartan failed to lower the risk of stroke, myocardial infarction, and vascular death compared with placebo in patients with atrial fibrillation (AF). However, irbesartan may have a role in preventing heart failure, recurrent embolic events, and cardiovascular hospitalizations in patients with AF.