<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cunningham, Muriel</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Adams, Robert J.</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Stroke in Sickle Cell Disease: Recent Successes</style></title><secondary-title><style face="normal" font="default" size="100%">MD Conference Express</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2008</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2008-04-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">25-26</style></pages><abstract><style  face="normal" font="default" size="100%">The reported incidence of all types of stroke in childhood is relatively low, with 2.6 occurring per 100,000 white children and 3.1 per 100,000 in black children [Broderick et al. Child Neurol 1993]. However, additional analyses indicate that children with sickle cell disease (SCD) face a huge relative risk of ischemic stroke compared with a healthy population (RR=220) [Earley et al. Neurology 1998]. Chronic blood transfusion therapy has been employed as secondary prevention of stroke in patients with SCD for over 30 years</style></abstract><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">8</style></volume></record></records></xml>