PT - JOURNAL ARTICLE AU - Jacobson, Anne ED - Jamerson, Kenneth A. TI - Data Suggest Approach to Hypertension Management Should Change DP - 2008 Jun 01 TA - MD Conference Express PG - 13--13 VI - 8 IP - 2 4099 - http://mdc.sagepub.com/content/8/2/13.short 4100 - http://mdc.sagepub.com/content/8/2/13.full AB - New data challenge the current guidelines for management of hypertension, which recommend initiating treatment with a diuretic and suggest monotherapy as the starting point of treatment. The ACCOMPLISH trial showed that a single-pill combination of an angiotensin-converting enzyme inhibitor and a calcium channel blocker led to excellent blood pressure control and significantly reduced the risk of cardiovascular events in high-risk patients.