Summary
In patients with grossly serosa-positive advanced gastric cancer, postoperative adjuvant chemotherapy with intraperitoneal cisplatin and early mitomycin C (M) plus long-term doxifluridine plus cisplatin (iceMFP) improved recurrence-free and overall survival. The comparator regimen in the phase 3 trial [AMC 0101] was M plus short-term doxifluridine.
- Gastrointestinal Cancers Clinical Trials
- © 2008 MD Conference Express
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A Randomized Phase 3 Trial of Intraperitoneal Cisplatin and Early Mitomycin C plus Long-Term Doxifluridine plus Cisplatin versus Mitomycin C plus Short-Term Doxifluridine
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