PT  - JOURNAL ARTICLE
AU  - Vinall, Maria
ED  - Emery, Paul
TI  - The RADIATE Study
DP  - 2008 Sep 01
TA  - MD Conference Express
PG  - 20--21
VI  - 8
IP  - 5
4099  - http://mdc.sagepub.com/content/8/5/20.short
4100  - http://mdc.sagepub.com/content/8/5/20.full
AB  - Although anti-TNF therapies are established treatments for rheumatoid arthritis (RA), significant proportions of patients do not achieve an adequate response, or become refractory to them. This article presents data from the RADIATE study [NCT00106522], a randomized, double-blind study that investigated the efficacy and safety of treatment with tocilizumab plus methotrexate in patients with moderate to severe RA and a prior history of failed anti-TNF therapy.