RT Journal Article
SR Electronic
A1 Vinall, Phil
T1 Novel Modular Analysis of Microarray Data to Follow Response to IL-1 Blockade in SoJIA Patients
JF MD Conference Express
YR 2008
FD SAGE Publications
VO 8
IS 5
SP 12
OP 12
DO 10.1177/155989770800800504
UL http://mdc.sagepub.com/content/8/5/12.abstract
AB Systemic onset JIA (SoJIA) is unique in terms of its clinical manifestations, prognosis, and response to therapy. This article presents results of a multicenter randomized double-blind trial [NCT00339157] conducted in patients with SoJIA where the objectives were to investigate immunological mechanisms underlying the disease and assess the effect of anakinra at a transcriptional level using patient blood transcriptional profiles.