PT - JOURNAL ARTICLE AU - Vinall, Phil ED - Allantaz, Florence TI - Novel Modular Analysis of Microarray Data to Follow Response to IL-1 Blockade in SoJIA Patients DP - 2008 Sep 01 TA - MD Conference Express PG - 12--12 VI - 8 IP - 5 4099 - http://mdc.sagepub.com/content/8/5/12.short 4100 - http://mdc.sagepub.com/content/8/5/12.full AB - Systemic onset JIA (SoJIA) is unique in terms of its clinical manifestations, prognosis, and response to therapy. This article presents results of a multicenter randomized double-blind trial [NCT00339157] conducted in patients with SoJIA where the objectives were to investigate immunological mechanisms underlying the disease and assess the effect of anakinra at a transcriptional level using patient blood transcriptional profiles.