RT Journal Article SR Electronic A1 Vinall, Maria T1 Intensive Lipid-Lowering Therapy with Simvastatin/Ezetimibe Combination Does Not Affect the Progression of Aortic Valve Stenosis: Results from the SEAS Study JF MD Conference Express YR 2008 FD SAGE Publications VO 8 IS 6 SP 25 OP 26 DO 10.1177/155989770800800616 UL http://mdc.sagepub.com/content/8/6/25.abstract AB Results from the Simvastatin and Ezetimibe in Aortic Stenosis [SEAS; NCT00092677] study indicate that intensive LDL-cholesterol-lowering with the combination of simvastatin 40 mg and ezetimibe 10 mg does not affect the progression of aortic valve stenosis, but can reduce the risk of cardiovascular ischemic events in subjects with mild-to-moderate asymptomatic aortic stenosis, when compared with placebo.