RT Journal Article SR Electronic A1 Canavan, Neil T1 Insulin Signaling, the CNS, and Longevity JF MD Conference Express YR 2008 FD SAGE Publications VO 8 IS 7 SP 31 OP 32 DO 10.1177/155989770800800716 UL http://mdc.sagepub.com/content/8/7/31.abstract AB Numerous recent studies of animal models suggest a highly active role for the central nervous system in energy homeostasis. While this is not surprising, an expansion of these findings indicates that insulin signaling has a pronounced influence on the lifespan of a wide array of organisms.