PT - JOURNAL ARTICLE AU - Canavan, Neil ED - BrĂ¼ning, Jens Claus TI - Insulin Signaling, the CNS, and Longevity DP - 2008 Nov 01 TA - MD Conference Express PG - 31--32 VI - 8 IP - 7 4099 - http://mdc.sagepub.com/content/8/7/31.short 4100 - http://mdc.sagepub.com/content/8/7/31.full AB - Numerous recent studies of animal models suggest a highly active role for the central nervous system in energy homeostasis. While this is not surprising, an expansion of these findings indicates that insulin signaling has a pronounced influence on the lifespan of a wide array of organisms.