RT Journal Article SR Electronic A1 Jacobson, Anne T1 Mitoglitazone and PPAR-Sparing Insulin Sensitizers JF MD Conference Express YR 2008 FD SAGE Publications VO 8 IS 7 SP 17 OP 19 DO 10.1177/155989770800800708 UL http://mdc.sagepub.com/content/8/7/17.abstract AB Activation of peroxisome proliferator-activated receptor (PPAR) is associated with dose-limiting side effects, such as edema and bone loss. This article describes recent efforts in the development of PPAR-sparing insulin sensitizers.