RT Journal Article SR Electronic A1 Cunningham, Muriel T1 Ranolazine Reduces Recurrent Ischemia in Patients with Non-ST Elevation ACS JF MD Conference Express YR 2007 FD SAGE Publications VO 7 IS 1 SP 20 OP 21 DO 10.1177/155989770700700110 UL http://mdc.sagepub.com/content/7/1/20.abstract AB Ranolazine is an anti-ischemic agent indicated for the treatment of chronic angina. Its effects occur without clinically significant changes in heart rate or blood pressure. However, because ranolazine is associated with a mild prolongation of the QTc interval (mean change approximately 6 ms), it currently is indicated only for patients who have not responded to other therapies. Because of this potentially worrisome prolongation of the QT interval, additional safety data were sought.