PT - JOURNAL ARTICLE AU - Cunningham, Muriel ED - Morrow, David A. TI - Ranolazine Reduces Recurrent Ischemia in Patients with Non-ST Elevation ACS DP - 2007 Jun 01 TA - MD Conference Express PG - 20--21 VI - 7 IP - 1 4099 - http://mdc.sagepub.com/content/7/1/20.short 4100 - http://mdc.sagepub.com/content/7/1/20.full AB - Ranolazine is an anti-ischemic agent indicated for the treatment of chronic angina. Its effects occur without clinically significant changes in heart rate or blood pressure. However, because ranolazine is associated with a mild prolongation of the QTc interval (mean change approximately 6 ms), it currently is indicated only for patients who have not responded to other therapies. Because of this potentially worrisome prolongation of the QT interval, additional safety data were sought.