PT  - JOURNAL ARTICLE
AU  - Helwick, Caroline
ED  - Freeman, Roy
TI  - Diabetic Peripheral Neuropathy: More Effective Treatments Needed
DP  - 2007 Dec 01
TA  - MD Conference Express
PG  - 26--27
VI  - 7
IP  - 6
4099  - http://mdc.sagepub.com/content/7/6/26.short
4100  - http://mdc.sagepub.com/content/7/6/26.full
AB  - In a pooled analysis of 1,510 patients enrolled in seven randomized controlled trials, pregabalin (150–600 mg/day) provided significant improvements in pain, sleep interference due to pain, and global health. Improvements in pain were dose-related; a clinically meaningful (=30%) improvement in pain was noted by 43%–62%, though 37% of placebo patients also reported this level of improvement.