RT Journal Article SR Electronic A1 Helwick, Caroline T1 Diabetic Peripheral Neuropathy: More Effective Treatments Needed JF MD Conference Express YR 2007 FD SAGE Publications VO 7 IS 6 SP 26 OP 27 DO 10.1177/155989770700700619 UL http://mdc.sagepub.com/content/7/6/26.abstract AB In a pooled analysis of 1,510 patients enrolled in seven randomized controlled trials, pregabalin (150–600 mg/day) provided significant improvements in pain, sleep interference due to pain, and global health. Improvements in pain were dose-related; a clinically meaningful (=30%) improvement in pain was noted by 43%–62%, though 37% of placebo patients also reported this level of improvement.