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type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/advagg_css\/css__ce2QY63WIanKyr8eSq7eavr1XQRRmFD6ZSmwpyJi8lM__zXwFqpqmxrZOXXcd_TpBQpjuELbmIP9wBR5UuTDWAO4__YJWWMMdfCJuAFm5cUEp88OsodhO3ZA-2lzRfoBsSlk4.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cdiv class=\u0022section abstract\u0022 id=\u0022abstract-1\u0022\u003E\u003Ch2\u003ESummary\u003C\/h2\u003E\n            \u003Cp id=\u0022p-1\u0022\u003EThis article discusses four independent studies have shown that doctors are failing to intensify therapy in people with type 2 diabetes and high blood glucose levels or high blood pressure.\u003C\/p\u003E\n         \u003C\/div\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003Ediabetes mellitus\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003Ehyperglycemia\/hypoglycemia\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003Ehypertensive disease\u003C\/li\u003E\u003C\/ul\u003E\u003Cdiv class=\u0022section\u0022 id=\u0022sec-1\u0022\u003E\n         \n         \u003Cp id=\u0022p-2\u0022\u003EFour independent studies have shown that doctors are failing to intensify therapy in people with type 2 diabetes and high blood glucose levels or high blood pressure. Physicians do not appear to be aware of the American Diabetes Association guidelines or choose not to follow them because, in the populations we studied, the antihypertensive regimen was intensified in only 26 percent of visits in which the individuals had elevated blood pressure,\u201d said Alexander Turchin, MD, MS, Brigham and Women\u0027s Hospital and Harvard Medical School, Boston, MA.\u003C\/p\u003E\n         \u003Cp id=\u0022p-3\u0022\u003EOther studies identified failure to intensify treatment to maintain blood glucose levels at the recommended A1C goal of less than 7%, and delay in therapy intensification for those on oral antidiabetic drugs on average until A1C was 8.5%.\u003C\/p\u003E\n      \u003C\/div\u003E\u003Cdiv class=\u0022section\u0022 id=\u0022sec-2\u0022\u003E\n         \u003Ch2 class=\u0022\u0022\u003EBrigham \u0026amp; Women\u0027s Hospital study\u003C\/h2\u003E\n         \u003Cp id=\u0022p-4\u0022\u003EThe Brigham and Women\u0027s Hospital study reviewed outpatient records of 1,244 hypertensive patients with type 2 diabetes and analyzed blood pressure data and evidence of antihypertensive therapy intensification. The study found that regimens were intensified at only 26% of visits where elevated blood pressure was documented. For every 10 mm of mercury of systolic pressure the probability of intensification of the antihypertensive regimen increased 40%; for every 10 mm of mercury of diastolic pressure, the probability increased 20%.\u003C\/p\u003E\n         \u003Cp id=\u0022p-5\u0022\u003EThe study also found that the younger the physician, the greater the probability that blood pressure medications would be intensified. Younger physicians, having just completed a residency, may be more aware of current ADA guidelines.\u003C\/p\u003E\n      \u003C\/div\u003E\u003Cdiv class=\u0022section\u0022 id=\u0022sec-3\u0022\u003E\n         \u003Ch2 class=\u0022\u0022\u003EThe Johns Hopkins study\u003C\/h2\u003E\n         \u003Cp id=\u0022p-6\u0022\u003EShari Bolen, MD, The Johns Hopkins University of Medicine, Baltimore, MD, stated that a Johns Hopkins study identified 1,374 type 2 diabetic patient visits with sub-optimally controlled blood pressure. Physicians intensified antihypertensive treatment in only 12% of visits. Physicians were twice as likely to intensify if the visit was routine, rather than urgent. Intensification was almost twice as likely if the person was seen by his\/her regular doctor instead of a covering provider.\u003C\/p\u003E\n         \u003Cp id=\u0022p-7\u0022\u003E\u201cSeveral factors were associated with a 40 to 50% lesser likelihood of intensification, including a higher glucose level or a history of coronary heart disease, suggesting in both instances that the physician focused on other clinical concerns to the detriment of attention to the hypertension problem,\u201d said Dr. Bolen.\u003C\/p\u003E\n      \u003C\/div\u003E\u003Cdiv class=\u0022section\u0022 id=\u0022sec-4\u0022\u003E\n         \u003Ch2 class=\u0022\u0022\u003EOral Anti-Diabetic Agents\u003C\/h2\u003E\n         \u003Cp id=\u0022p-8\u0022\u003ENovartis Pharmaceutical Corporation studied the prescribing pattern of oral antidiabetic drugs using a retrospective analysis of the pharmacy and lab claims of a commercial PPO model of a national managed care organization. The study identified 9,416 type 2 diabetics who had received a first prescription of metformin, a sulfonylurea or a thiazolidinedione. The study only looked at claims, not physician notes.\u003C\/p\u003E\n         \u003Cp id=\u0022p-9\u0022\u003EThe average time to therapy intensification, when another medication was added, was 240 days. By that time, according to Craig A. Plauschinat, PharmD, MPH, Outcomes Research Manager at Novartis, the average A1C was 8.5%, but 67% of these individuals had A1C levels near 10%\u003C\/p\u003E\n         \u003Cp id=\u0022p-10\u0022\u003E\u201cDisturbingly, 50% of those who were intensified did not have an A1C in their charts prior to the addition of a second drug,\u201d stated Dr. Plauschinat. \u201cIt is unknown how the physician made the decision to add a second drug in the absence of A1C testing, although it is possible the decision was based on a finger stick glucose test in the office or patient reports of home blood glucose testing.\u201d Clinical inertia maybe an important barrier to effective diabetes treatment. The identification of factors contributing to clinical inertia will allow physicians and the ADA to design interventions aimed at increasing treatment intensity and improving outcomes, according to Dr. Turchin.\u003C\/p\u003E\n      \u003C\/div\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2006 MD Conference Express\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Ca href=\u0022http:\/\/mdc.sagepub.com\/content\/6\/2\/31.abstract\u0022 class=\u0022hw-link hw-link-article-abstract\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView Summary\u003C\/a\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzm641\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}