<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vinall, Maria</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Nishimoto, Norihiro</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Efficacy and Safety of Tocilizumab in Monotherapy, an Anti-II-6 Receptor Monoclonal Antibody, in Patients with Active Rheumatoid Arthritis: Results from a 24 Week Double-Blind Phase III Study</style></title><secondary-title><style face="normal" font="default" size="100%">MD Conference Express</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2006</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2006-09-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">14-14</style></pages><abstract><style  face="normal" font="default" size="100%">The efficacy and safety of tocilizumab, an anti-IL-6 receptor monoclonal antibody, was examined as a monotherapy in patients with active RA who had inadequate responses to MTX. In this Japanese study, RA patients previously treated with MTX received either tocilizumab 8 mg/kg every 4 weeks + a MTX placebo (tocilizumab group) or a tocilizumab placebo + MTX 8 mg/week (MTX group) for 24 weeks.</style></abstract><number><style face="normal" font="default" size="100%">3</style></number><volume><style face="normal" font="default" size="100%">6</style></volume></record></records></xml>