PT - JOURNAL ARTICLE AU - Alexander, Walter ED - Kitakaze, Masafumi TI - Effects of Carperitide and Nicorandil on Injury and Function in Patients with Acute MI: Results of the J-WIND Trial DP - 2006 01 TA - MD Conference Express PG - 17--20 VI - 6 IP - 5 4099 - http://mdc.sagepub.com/content/6/5/17.short 4100 - http://mdc.sagepub.com/content/6/5/17.full AB - The results of the Japanese Working Groups of Acute Myocardial Infarction for the Reduction of Necrotic Damage by Atrial Natriuretic Peptide (ANP) or Nicorandil [J-WIND] trials conducted in Japan from 2001–2006. Carperitide, human recombinant ANP, is approved for the treatment of acute heart failure in Japan. Nicorandil, a nicotinamide nitrate that activates potassium channels in the heart, is used to treat chronic angina. These randomized, double-blind studies evaluated intervention with either carperitide or nicorandil on infarct size, left ventricular function, and associated outcomes.