PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Röllig, Christoph TI - Sorafenib as Effective Treatment for Newly Diagnosed AML in Younger Patients DP - 2014 01 TA - MD Conference Express PG - 8--9 VI - 14 IP - 55 4099 - http://mdc.sagepub.com/content/14/55/8.2.short 4100 - http://mdc.sagepub.com/content/14/55/8.2.full AB - Acute myeloid leukemia, a common form of leukemia with a high mortality rate, is difficult to treat. In the SORAML trial, sorafenib, a multikinase inhibitor, prolonged event-free and relapse-free survival compared with a placebo in younger patients with acute myeloid leukemia. However, this benefit was accompanied by a higher rate of infections and bleeding.