PT  - JOURNAL ARTICLE
AU  - Vinall, Maria
ED  - Amant, Frederic
TI  - Phase 3 Trial to Compare Postoperative Chemotherapy with Observation in Stage I or II Endometrial Cancer
DP  - 2014 Dec 01
TA  - MD Conference Express
PG  - 20--21
VI  - 14
IP  - 36
4099  - http://mdc.sagepub.com/content/14/36/20.short
4100  - http://mdc.sagepub.com/content/14/36/20.full
AB  - Patients with stage I or II endometrial cancer are generally treated with surgery. Despite radical surgery, however, patients with medium- or high-risk stage I and II endometrial cancers are still at significant risk of local and distant progression. A current phase 3 study [NCT01244789] is preparing to evaluate whether survival can be improved in intermediate- and high-risk early-stage patients by offering postoperative chemotherapy instead of postoperative observation alone (standard strategy), as discussed in this article.