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type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/cdn\/css\/http\/css_Xg7z6oCTVgud_Q0huYz9x9iiD5H_2YPSJ5z2ZViSWdY.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cdiv class=\u0022section abstract\u0022 id=\u0022abstract-1\u0022\u003E\u003Ch2\u003ESummary\u003C\/h2\u003E\n            \u003Cp id=\u0022p-1\u0022\u003EIntensity-modulated radiation therapy (IMRT) and 3-dimensional conformal radiation therapy (3DCRT) are common radiation methods used to treat patients with esophageal cancer. Esophageal carcinoma treatment response to IMRT was not significantly different from 3DCRT, according to results discussed this retrospective analysis article.\u003C\/p\u003E\n         \u003C\/div\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003ERadiation Therapy\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EOncology Clinical Trials\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003ERadiology\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EGastrointestinal Cancers\u003C\/li\u003E\u003C\/ul\u003E\u003Cul class=\u0022kwd-group clinical-trial\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003ERadiation Therapy\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EOncology Clinical Trials\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003ERadiology\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EOncology\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EGastrointestinal Cancers\u003C\/li\u003E\u003C\/ul\u003E\u003Cp id=\u0022p-2\u0022\u003EEsophageal carcinoma treatment response to intensity-modulated radiation therapy (IMRT) was not significantly different from 3-dimensional conformal radiation therapy (3DCRT). Jie Kong, MD, Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China, presented results from this retrospective analysis.\u003C\/p\u003E\u003Cp id=\u0022p-3\u0022\u003EIMRT and 3DCRT are common radiation methods used to treat patients with esophageal cancer at Dr Kong\u0027s institution. This retrospective study examined differences in patient response and the extent of dosage to organs at risk (OAR) of these targeted radiation techniques.\u003C\/p\u003E\u003Cp id=\u0022p-4\u0022\u003ETreatment response, overall survival, and dosage of OAR were assessed in 510 consecutive patients. Most patients had squamous cell esophageal carcinoma (92.8%). At the discretion of the radiation oncologist, IMRT was administered to 66 patients and 3DCRT to 444 patients. Regardless of method, patients received roughly 2 Gy per day, 5 days a week and may have received concurrent and\/or subsequent chemotherapy.\u003C\/p\u003E\u003Cp id=\u0022p-5\u0022\u003EThere were no significant differences in any of the measured outcomes between IMRT and 3DCRT. Overall survival rates were similar (27.3% vs 23.4%), as were 1-year (72.7% vs 68.2%) and 5-year (32.3% vs 25.5%) survival rates. Although the complete response rate for patients treated with IMRT was slightly higher than 3DCRT (60.6% vs 53.2%), it was not statistically different.\u003C\/p\u003E\u003Cp id=\u0022p-6\u0022\u003EThe dosage of OAR in the lung and heart showed no overall differences, but there was less variation for IMRT vs 3DCRT. The median percentage of pulmonary volume receiving radiation \u0026gt; 20 Gy for IMRT) was similar to 3DCRT (25.2 vs 24) but showed less variation (Q1-Q3 range, 22.6\u201326.9 for IMRT vs 18.6\u201327.4 for 3DCRT). The V40 for the heart was also more variable with IMRT (median 20.2; range, 5.9\u201328.4) compared with 3DCRT (median 17.3; range, 11.2\u201340.4).\u003C\/p\u003E\u003Cp id=\u0022p-7\u0022\u003EDr Kong concluded that IMRT was no more effective than 3DCRT, but further investigation of the variability of dosage of OAR may be warranted.\u003C\/p\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2014 MD Conference Express\u00ae\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Ca href=\u0022http:\/\/mdc.sagepub.com\/content\/14\/31\/16.1.abstract\u0022 class=\u0022hw-link hw-link-article-abstract\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView Summary\u003C\/a\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzm01q\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}