PT - JOURNAL ARTICLE AU - Busse, Gregory ED - Duman, Ronald S. TI - Depression Overview DP - 2007 Aug 01 TA - MD Conference Express PG - 28--29 VI - 7 IP - 2 4099 - http://mdc.sagepub.com/content/7/2/28.short 4100 - http://mdc.sagepub.com/content/7/2/28.full AB - This article provided preclinical and clinical evidence on the role of brain derived neurotrophic factor (as well as other neurotrophic factors) in major depressive disorder. Also discussed is the continuation and discontinuation of venlaxafine and its metabolite in refractory depressed patients.