PT  - JOURNAL ARTICLE
AU  - Gater, Laura
ED  - Mandrup-Poulsen, Thomas
TI  - IL-1 Receptor Antagonist Therapy in Type 2 Diabetes
DP  - 2006 Sep 01
TA  - MD Conference Express
PG  - 14--14
VI  - 6
IP  - 2
4099  - http://mdc.sagepub.com/content/6/2/14.short
4100  - http://mdc.sagepub.com/content/6/2/14.full
AB  - Impaired β-cell function and decreased β-cell mass due to apoptosis contribute to impaired insulin secretion in patients with type 2 diabetes. Interleukin-1 receptor antagonists (IL-1Ra) can block β-cell apoptosis, and patients with type 2 diabetes are known to have reduced levels of IL-1Ra expression. This article presents results from a recent study examining anakinra in the treatment of type 2 diabetes.