<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors></authors><secondary-authors><author><style face="normal" font="default" size="100%">Creager, Mark</style></author><author><style face="normal" font="default" size="100%">Diaz, Raphael</style></author><author><style face="normal" font="default" size="100%">Schneider, David J.</style></author><author><style face="normal" font="default" size="100%">Nesto, Richard</style></author><author><style face="normal" font="default" size="100%">Connolly, Mark</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Metabolic Management of the Patient with Ischemic Heart Disease: Diabetes and Metabolic Syndrome</style></title><secondary-title><style face="normal" font="default" size="100%">MD Conference Express</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2006</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2006-04-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">29-29</style></pages><abstract><style  face="normal" font="default" size="100%">“Let's get one thing clear,” said Mark Creager, MD, Harvard Medical School. “Diabetes is a cardiovascular disorder.” Dr. Creager reviewed links between hyperglycemia and endothelial dysfunction, including the interplay of free fatty acids that increase oxidative stress. “Hyperglycemia activates signaling events at the endothelial level we'd just as soon never got started,” he said. “Ultimately, hyperglycemia has a direct effect on thrombosis and fibrinolysis.”</style></abstract><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">6</style></volume></record></records></xml>