RT Journal Article SR Electronic T1 What You Need to Know about Degenerative Mitral Valve Regurgitation in 2006 JF MD Conference Express YR 2006 FD SAGE Publications VO 6 IS 1 SP 24 OP 24 DO 10.1177/155989770601013 UL http://mdc.sagepub.com/content/6/1/24.abstract AB “Myxoid changes are the leading cause of mitral valve (MV) prolapse and regurgitation,” according to Brian Griffin, MD, Cleveland Clinic. Myxoid chordae in MR have <25% of normal load bearing capacity, Dr. Griffin noted. “But are these myxomatous changes genetically programmed or maladaptative?” Dr. Griffin asked. “More studies are needed to help answer this question”