PT - JOURNAL ARTICLE ED - Griffin, Brian ED - Rosenhek, Raphael ED - Bonow, Robert O. ED - Schwartz, Allan TI - What You Need to Know about Degenerative Mitral Valve Regurgitation in 2006 DP - 2006 May 01 TA - MD Conference Express PG - 24--24 VI - 6 IP - 1 4099 - http://mdc.sagepub.com/content/6/1/24.short 4100 - http://mdc.sagepub.com/content/6/1/24.full AB - “Myxoid changes are the leading cause of mitral valve (MV) prolapse and regurgitation,” according to Brian Griffin, MD, Cleveland Clinic. Myxoid chordae in MR have <25% of normal load bearing capacity, Dr. Griffin noted. “But are these myxomatous changes genetically programmed or maladaptative?” Dr. Griffin asked. “More studies are needed to help answer this question”