PT  - JOURNAL ARTICLE
AU  - Hoyle, Brian
ED  - Stratton, Michael
TI  - Mutational Signatures in Human Cancer
DP  - 2014 Dec 01
TA  - MD Conference Express
PG  - 4--5
VI  - 14
IP  - 36
4099  - http://mdc.sagepub.com/content/14/36/4.short
4100  - http://mdc.sagepub.com/content/14/36/4.full
AB  - To date, 10 000 to 20 000 cancer genomes have been fully or partially sequenced. Cancer genome sequences could prove crucial in predicting therapy outcome and response and could allow the development of assays that detect sequence fragments that leak out of cancer cells. It is hoped that these fragments will prove to be diagnostic hallmarks. This article discusses the mutational signatures of human cancer.