RT Journal Article
SR Electronic
A1 Nichols, Emma Hitt
T1 New Members of the Leptin–Melanocortin Axis Linked to Pediatric Obesity
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 20
SP 26
OP 27
DO 10.1177/155989771420015
UL http://mdc.sagepub.com/content/14/20/26.abstract
AB Proper function of the leptin–melanocortin axis is important in regulating food intake and maintaining energy homeostasis. Therefore, mutations that affect the leptin–melanocortin axis result in several known syndromes that result in an obesity phenotype. Recent research has further identified important components of this axis that may result in childhood-onset obesity as discussed in this article.