Summary

The 2 currently available categories of osteoporosis therapies are the antiresorptive agents, which decrease bone resorption and bone formation, and parathyroid hormone agonists, which increase bone formation and bone resorption. Cathepsin K inhibition is a new mechanism of action that inhibits bone resorption while preserving bone formation.

  • anabolic
  • bone formation
  • bone remodeling
  • bone resorption
  • cathepsin K
  • osteoporosis
  • parathyroid hormone
  • parathyroid hormone-related protein
  • postmenopausal
  • RANKL
  • sclerostin
  • hormone therapy
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