Summary
The 2 currently available categories of osteoporosis therapies are the antiresorptive agents, which decrease bone resorption and bone formation, and parathyroid hormone agonists, which increase bone formation and bone resorption. Cathepsin K inhibition is a new mechanism of action that inhibits bone resorption while preserving bone formation.
- anabolic
- bone formation
- bone remodeling
- bone resorption
- cathepsin K
- osteoporosis
- parathyroid hormone
- parathyroid hormone-related protein
- postmenopausal
- RANKL
- sclerostin
- hormone therapy
- © 2015 SAGE Publications