PT - JOURNAL ARTICLE AU - Boltz, Kathy ED - Shen, Guoxiang TI - The PAOLA Study DP - 2015 Jun 18 TA - MD Conference Express PG - 8--10 VI - 15 IP - 4 4099 - http://mdc.sagepub.com/content/15/4/8.2.short 4100 - http://mdc.sagepub.com/content/15/4/8.2.full AB - Pasireotide LAR had a dose-proportional relationship with dose exposure over a 40- to 60-mg range. Efficacy end points of levels of growth hormone and IGF-1 were correlated with pasireotide exposure, and response rates were higher at the higher pasireotide dose.