PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Falagas, Matthew E. TI - Compliance Higher With Once-Daily Antibiotic Administration vs Multiple Times a Day DP - 2015 Jul 23 TA - MD Conference Express PG - 21--21 VI - 15 IP - 48 4099 - http://mdc.sagepub.com/content/15/48/21.short 4100 - http://mdc.sagepub.com/content/15/48/21.full AB - A number of small studies have indicated that once-daily administration of an antibiotic is just as effective as multiple daily doses. In this meta-analysis using studies in adults and children, the relative risk for compliance with antibiotic treatment was higher with once-daily dosing compared with dosing two, three, or four times daily.