RT Journal Article
SR Electronic
A1 Zarifyan, Alla
T1 Persistent Atrial Fibrillation
JF MD Conference Express
YR 2015
FD SAGE Publications
VO 15
IS 12
SP 22
OP 23
DO 10.1177/1559897715593520
UL http://mdc.sagepub.com/content/15/12/22.abstract
AB Atrial fibrillation can become self-sustaining due to structural remodeling that results in changes in ion currents over time. Treatment of atrial fibrillation with ablation does not appear to be improved by additional substrate ablation (CFE or Lines) when performed in addition to PVI. There is also mounting evidence for the role of rotors in AF. Many patients experience termination of atrial fibrillation following ablation of rotor sites, suggesting that therapies that target rotors may be one approach to reduce the burden of AF.