PT  - JOURNAL ARTICLE
AU  - Summers, Jaye
ED  - Saxena, Varun
TI  - Simeprevir + Sofosbuvir Effective in Patients With Moderate to Severe Cirrhosis
DP  - 2015 Sep 07
TA  - MD Conference Express
PG  - 18--19
VI  - 15
IP  - 14
4099  - http://mdc.sagepub.com/content/15/14/18.short
4100  - http://mdc.sagepub.com/content/15/14/18.full
AB  - There are few data regarding the efficacy and safety of simeprevir + sofosbuvir in patients with decompensated cirrhosis. Data from this study comparing this drug combination in patients with Child-Pugh B/C cirrhosis with patients who received older treatment regimens suggest that recently approved all-oral therapies offer patients with decompensated cirrhosis a safer and more effective therapy than historical peginterferon-based therapies.