RT Journal Article SR Electronic A1 Lederman, Lynne T1 Eluxadoline Shows Efficacy for IBS-D in IBS3001 and IBS3002 Phase 3 Trials JF MD Conference Express YR 2015 FD SAGE Publications VO 15 IS 14 SP 12 OP 13 DO 10.1177/1559897715593926 UL http://mdc.sagepub.com/content/15/14/12.2.abstract AB Eluxadoline, a ยต-opioid receptor agonist and d-opioid receptor antagonist, exhibits rapid onset of action along with sustained efficacy over the 6-month treatment period as studied in the phase 3, double-blind, placebo-controlled IBS3001 and IBS3002 trials in patients with diarrhea-predominant irritable bowel syndrome.